The thyroid makes inactive hormone T4. Most of the T4 is converted to the active hormone free T3 in the liver, and some in the gut.
Reverse T3 is also converted at the same time, and acts as a brake in times when the body needs to conserve resources, such as starvation.
Too high levels of Reverse T3 prevent the body from absorbing enough free T3 to the cells. This is why it’s important to test reverse t3 along with free T3.
High reverse T3 can be caused by T4-only medications such as Synthroid and Levothyroxine.
What are some side effects of high reverse T3? Dry skin and hair, fatigue, weight gain, menstrual difficulties, constipation, etc.
Lowering reverse T3 often takes a multi-pronged approach. We need to look at iron and cortisol closely along with our medication. Sometimes a T3-only medication such as Cytomel or generic or compounded liothyronine.
It’s important to work on the liver to clean out old bile, sludge and stones. Beet powder capsules are an excellent, gentle solution.
Working on the gut is also important. It is suggested to go on an anti-inflammatory diet such as Paleo or Autoimmune Protocol.